Scientific Publications

 

Publications from MEDINA during the last 5 years

 

2013

 

  • Bastien Cautain, Nuria de Pedro, Victor González Menéndez, José R. Tormo, Jesús Martin, Noureddine El Aouad, Olga Genilloud, Francisca Vicente Pérez, Wolfgang Link (2013) A cell-based strategy using high-content imaging for the discovery of novel nuclear export inhibitors from natural products. Journal Biomolecular screening (in press).

  • Bastien Cautain, Nuria de Pedro, Maria Muñoz de Escalona, Jose R. Tormo, Olga Genilloud, Francisca Vicente (2013) HCS Strategy Targeting Dysregulation Of The VHL/HIF Pathway For Drug Discovery. Advances in Bioscience and Biotechnology (in press).

  • Bastien Cautain, Richard Hill, Nuria de Pedro & Wolfgang Link (2013) Targeting Nucleocytoplasmic Transport in Cancer Therapy. Oncotarget (in press).

  • Olga Genilloud, Sara Palomo, Ignacio González, Jesús Martín, Mercedes de la Cruz, Francisca Vicente, Fernando Reyes, José Rubén Tormo, Matthew Anderson, Russell T. Hill (2013) Sponge-derived Kocuria and Micrococcus spp. as new sources of thiazolylpeptide antibiotics. Marine Drugs (in press)

  • Lin Zhang, Anjaneya S. Ravipati, Sundar R Koyyalamudi, Sang Chul Jeong, Narsimha Reddy, John Bartlett, Paul T. Smith, Mercedes de la Cruz, Maria Cândida Monteiro, Ángeles Melguizo, Ester Jiménez, Francisca Vicente. Anti-fungal and anti-bacterial activities of ethanol extracts of selected traditional Chinese medicinal herbs. Asian Pacific Journal of Tropical Medicine (in press).
  • Sheo B. Singh John Ondeyka, Guy Harris, Kithsiri Herath, Deborah Zink, Francisca Vicente, Gerald Bills, Javier Collado, Gonzalo Platas, Antonio González de Val, Jesus Martin, Fernando Reyes, Hao Wang, Jennifer Nielsen Kahn, Stefan Galuska, Robert Giacobbe, George Abruzzo, Terry Roemer, Deming Xu. (2012) Isolation, structure and biological activity of a cyclic lipodepsipeptide phaeofungin from a Phaeosphaeria sp. using the genome-wide Candida albicans Fitness Test. Journal of Natural Products (in press).

  • Elena García, Ángela Alonso, Gonzalo Platas & Soledad Sacristán. (2013) The endophytic mycobiota of Arabidopsis thaliana. Fungal diversity (in press).

  • Nuria de Pedro,  Bastien Cautain,  Angeles Melguizo,  Francisca Vicente,  Olga Genilloud,  Fernando Peláez,  Jose R. Tormo (2013) Mitochondrial complex I inhibitors, acetogenins, induce 5 HepG2 cell death through the induction of the complete 6 apoptotic mitochondrial pathway. J Bioenerg Biomembr  45, Issue 1-2: 153-164.
  • Nuria de Pedro Montejo, Bastien Cautain,  Angeles Melguizo,  Diego Cortes,  Francisca Vicente,   Olga Genilloud,  Jose R. Tormo,  Fernando Peláez (2013) Analysis of cytotoxic activity at short incubation times reveals profound differences among Annonaceus acetogenins, inhibitors of mitochondrial Complex I. J Bioenerg Biomembr  45, Issue 1-2, pp 145-152.

  • Jesús Martín, Thiciana da S Sousa, Gloria Crespo, Sara Palomo, Ignacio González, José R Tormo, Mercedes de la Cruz, Matthew Anderson, Russell T Hill, Francisca Vicente, Olga Genilloud, Fernando Reyes (2013) Kocurin, the True Structure of PM181104, an Anti-Methicillin-Resistant Staphylococcus aureus (MRSA) Thiazolyl Peptide from the Marine-Derived Bacterium Kocuria palustris. Marine Drugs 11(2): 387-98.

  • Anjaneya S. Ravipati, Lin Zhang, Sundar R Koyyalamudi, Sang Chul Jeong, Narsimha Reddy, John Bartlett, Paul T. Smith, Nuria de Pedro, Ángeles Melguizo, Juan Cantizani, Francisco Asensio, Francisca Vicente (2013) Anti-proliferative activities of selected Chinese medicinal herbs against human cancer cell lines. Phytopharmacology 2013, 4(2), 206-219.

 

2012

 

  • Sheo B Singh, Michael A Goetz, Scott K Smith, Deborah L Zink, Jon Polishook, Russell Onishi, Scott Salowe, Judyann Wiltsie, John Allocco, Janet Sigmund, Karen Dorso, Mercedes de la Cruz, Jesús Martín, Francisca Vicente, Olga Genilloud, Robert G K Donald, John W Phillips (2012)  Kibdelomycin A, a congener of kibdelomycin, derivatives and their antibacterial activities. Bioorganic & medicinal chemistry letters 22(23):7127-7130.
  • Teresa Fernández-Acero, Isabel Rodríguez-Escudero, Francisca Vicente, Maria Cândida Monteiro, José R Tormo, Juan Cantizani, María Molina, Víctor J Cid (2012) A yeast-based in vivo bioassay to screen for class I phosphatidylinositol 3-kinase specific inhibitors. Journal of Biomolecular Screening 17(8):1018-1029.
  • Mª Francisca Vicente, Gerald Bills, Fernando Reyes, Olga Genilloud (2012) Fundación MEDINA - Investigación en Terapias Innovadoras a partir de Productos Naturales aislados de Microorganismos. Especial Microbiología Industrial y Biotecnología Microbiana. Actualidad SEM 53, 32-35.
  • Marco Kai, Ignacio González, Olga Genilloud, Sheo B Singh, Aleš Svatoš (2012) Direct mass spectrometric screening of antibiotics from bacterial surfaces using liquid extraction surface analysis. Rapid communications in mass spectrometry 26(20):2477-2482.
  • Olga Genilloud (2012) Current Challenges in the Discovery of Novel Antibacterials from Microbial Natural Products. Recent Patents on Anti-Infective Drug Discovery  7,  3, pp. 189-204(16)
  • Bills, GF, González-Menéndez, V, Martin, J, Platas, G, Fournier, J, Peršoh, D and Stadler, M. Hypoxylon pulicicidum sp. nov. (Ascomycota, Xylariales), a Pantropical Insecticide-Producing Endophyte . PLOS One, 7, e46687
  • Bills, GF, González-Menéndez, V and Platas, G (2012) Kabatiella bupleuri sp. nov. (Dothideales), a pleomorphic epiphyte and endophyte of the Mediterranean plant, Bupleurum gibraltarium (Apiaceae). Mycologia 104, 962-973
  • Cueva, C, Garcia Ruiz, A, González-Rompinelli, Bartolomé, EB, Martín-Álvarez, PJ, Salazar, O, Vicente, MF,  Bills, G and  Moreno-Arribas, V (2012) Degradation of biogenic amines by vineyard ecosystem fungi. Potential use in winemaking. Journal of Applied Microbiology 112, 672-682
  • de la Cruz, M, Martín, J, González-Menéndez, V,  Pérez-Victoria, I, Moreno, C, Tormo, JR, El Aouad, N Guarro, J, Vicente, F, Reyes, F and Bills, GF (2012) Chemical and physical modulation of antibiotic activity in Emericella species. Chemistry & Biodiversity 9, 1095-1113
  • El Aouad, N, Pérez-Moreno, G, Sánchez, P, Cantizani, J, Ortiz-López, FJ, Martín, J, González-Menéndez, V, Ruiz-Pérez, LM, González-Pacanowska, D, Vicente, F, Bills, G and Reyes, F (2012) Lasionectrin, a Naphthopyrone from a Lasionectria sp. Journal of Natural Products 75, 1228-1230
  • Genilloud, O and Vicente F (2012) Novel approaches to exploit natural products from microbial resources.  In Drug Discovery from Natural Products, Eds. O. Genilloud and F. Vicente, RSC series. Ch. 11, pp. 221-248
  • Genilloud, O (2012) Genus Micromonospora. In Bergey's Manual of Systematic Bacteriology, Volume 5 (Actinobacteria) eds. Busse, H-J, Goodfellow, M, Kämpfer, P, Ludwig, W, Suzuki, K and Whitman, WB. p. vol 5 B, 1039-1057
  • Genilloud, O (2012) Suborder XI. Micromonosporineae and The family Micromonosporaceae. In Bergey's Manual of Systematic Bacteriology, Volume 5 (Actinobacteria) eds. Busse, H-J, Goodfellow, M, Kämpfer, P, Ludwig, W, Suzuki, K and Whitman, WB. p. vol 5 B, 1035-1038
  • Herath, K, Jayasuriya, H, Zink, DL,  Sigmund, J, Vicente, F,  de la Cruz, M,  Basilio, A, Bills, GF, Polishook, JD, Donald, R, Phillips, J,  Goetz, M and Singh, SB (2012) Isolation, structure elucidation and antibacterial activity of methiosetin, a new tetramic acid from a tropical sooty mold (Capnodium sp.). Journal of Natural Products 75, 420–424
  • Monteiro, MC, de la Cruz, M, Cantizani, J, Moreno, C, Tormo, JR,  Mellado, E,  de Lucas, JR, Asensio, F,  Valiante, V, Brakhage, AA, Latgé, J-P, Genilloud, O and Vicente, F (2012) A New Approach to Drug Discovery: High-Throughput Screening of Microbial Natural Extracts against Aspergillus fumigatus Using Resazurin. Journal of Biomolecular Screening 17, 542-549
  • Pérez-Victoria, I, Martín, J, González-Menéndez, V, de Pedro,, N, El Aouad, N, Ortiz-López, FJ, Tormo, JR, Platas, G, Vicente, F, Bills, GF, Genilloud, O, Goetz, MA and Reyes, F (2012) Isolation and Structural Elucidation of Cyclic Tetrapeptides from Onychocola sclerotica. Journal of Natural Products 75, 1210-1214
  • Sánchez-Hidalgo, M, Pascual, J, de la Cruz, M, Martín, J, Kath, GS, Sigmund, JM, Masurekar, P, Vicente, F, O. Genilloud, O and Bills, GF (2012) Prescreening bacteria colonies for bioactive molecules with Janus plates, a SBS standard double-faced microbial culturing system. Antonie van Leeuwenhoek 102, 361-374
  • Montalbán-López, M, Sánchez-Hidalgo, M, Cebrián, R, and Maqueda, M (2012) Discovering the Bacterial Circular Proteins: bacteriocins, cyanobactins, and pilins. J. Bio. Chem. 287, 27007–27013
  • Tormo, JR, Asensio, FJ and Bills (GF) (2012) Manipulating filamentous fungus chemical phenotypes by growth in nutritional arrays. In Methods in Molecular Biology Fungal Secondary Metabolism: Methods and Protocols, Nancy P. Keller and Geoffrey Turner (eds.), Methods in Molecular Biology, vol. 944, Ch. 4, pp. 59-78
  • Oves-Costales, D and Challis GL (2012) Mining microbial genomes for metabolic products of cryptic pathways. In Drug Discovery from Natural Products, Eds. O. Genilloud and F. Vicente, RSC series. Ch. 8, pp. 140-158
  • Nusca, TD, Kim, Y, Maltseva, N, Lee, JY, Eschenfeldt, W, Stols, L, Schofield, MM, Scaglione, JB, Dixon, SD, Oves-Costales, D, Challis, GL, Hanna, PC, Pfleger, BF, Joachimiak, A, Sherman, DH (2012) Functional and structural analysis of the siderophore synthetase AsbB through reconstitution of the petrobactin biosynthetic pathway from Bacillus anthracis. Journal of Biological Chemistry 287, 16058-16072

  • F. L. S. Sebastianes, N. Cabedo, N. El Aouad, A. M. M. P. Valente, P. T. Lacav, J. L. Azevedo, A. A. Pizzirani-Kleiner, and D. Cortés (2012) Current Microbiology, vol. 65, 622-632

 

2011

 

  • Ferrer, M.,  M.-E. Guazzaroni,  M. Richter, A. García-Salamanca,  P. Yarza,  A. Suárez-Suárez,  J. Solano, M. Alcaide, P. van Dillewijn, M. A. Molina-Henares, N. López-Cortés, Y. Al-Ramahi, C. Guerrero, A. Acosta, L. I. de Eugenio, V. Martínez, S. Marques, F. Rojo, E. Santero, O. Genilloud, J. Pérez-Pérez, R. Rosselló-Móra, J.L. Ramos. (2011) Taxonomic and Functional Metagenomic Profiling of the Microbial Community in the Anoxic Sediment of a Sub-saline Shallow Lake (Laguna de Carrizo, Central Spain). Microbial Ecology 62: 824-37
  • Cueva, C.; V. Moreno-Arribas, B. Bartolomé, O. Salazar, M.F. Vicente & G.F. Bills. 2011. Antibiosis of vineyard ecosystem fungi against food-borne microorganisms. Research in Microbiology 162: 1043–1051.
  • Torres, M.S., M. Tadych, J.F. White, Jr. & G.F. Bills. 2011. Dilution-to-extinction cultivation of endophytic fungi and isolation and detection of grass endophytic fungi in different plant parts, Isolation and identification of fungal endophytes. Pgs. 13-18, 153-164. In: Prospects and Applications for Plant-Associated Microbes. A Laboratory Manual, Part B: Fungi. Editors A.M. Pirttilä & S. Sorvari. BioBien Innovations, Paimio, Finland.
  • Ignacio Pérez-Victoria, Francisco J. Pérez-Victoria, Sándalo Roldán-Vargas, Raquel García-Hernández, Luis Carvalho  Santiago Castanys, Francisco Gamarro, Juan C. Morales, José M. Pérez-Victoria, (2011) Non-reducing trisaccharide fatty acid monoesters: Novel detergents in membrane biochemistry. Biochimica et Biophysica Acta 1808: 717–726
  • S. Sánchez Márquez, G.F. Bills & I. Zabalgogeazcoa (2011) Fungal species diversity in juvenile and adult leaves of Eucalyptus globulus from plantations affected by Mycosphaerella leaf disease. Annals of Applied Biology 158:177-187
  • Jenny Campos-Salinas, María Cabello-Donayre, Raquel García-Hernández, Ignacio Pérez-Victoria, Santiago Castanys, Francisco Gamarro and José M. Pérez-Victoria (2011) A new ATP binding cassette protein is involved in intracellular haem trafficking in Leishmania. Molecular Microbiology doi:10.1111/j.1365-2958.2010.07531.x
  • Olga Genilloud, Ignacio González, Oscar Salazar, Jesus Martín,  José Rubén Tormo, Francisca Vicente (2011) Current approaches to exploit actinomycetes as a source of novel natural products. J Ind Microbiol Biotechnol 38:375–389
  • Terry Roemer, Deming Xu, Sheo B. Singh, Craig A. Parish, Guy Harris, Hao Wang, Julian E. Davies and Gerald F. Bills Confronting the Challenges of Natural Product-Based Antifungal Discovery (2011) Chemistry & Biology 18:148-164.
  • Deming Xu, John Ondeyka, Guy H. Harris, Deborah Zink, Jennifer Nielsen Kahn, Hao Wang, Gerald Bills, Gonzalo Platas, Wenxian Wang, Alexander A. Szewczak, Paul Liberator, Terry Roemer, and Sheo B. Singh (2011) Isolation, Structure, and Biological Activities of Fellutamides C and D from an Undescribed Metulocladosporiella (Chaetothyriales) Using the Genome-Wide Candida albicans Fitness Test. J. Nat. Prod. 2011
  • Gabriel Moreno, Maria-Natividad Blanco, Julia Checa,  Gonzalo Platas,  Fernando Peláez (2011) Taxonomic and phylogenetic revision of three rare irpicoid species within the Meruliaceae. Mycol Progress 10: 481-491.
  • Peláez, F, Collado, J, Platas, G, Overy, DP, Martín, J, Vicente, F, González del Val, A, Basilio, A, de la Cruz, M, Tormo, JR, Fillola, A, Arenal, F, Villareal, M, V. Rubio, Baral, HO, Galán, R and Bills, GF (2011) The phylogeny and intercontinental distribution of the pneumocandin-producing anamorphic fungus Glarea lozoyensis. Mycology, 2: 1–17.
  • John W. Phillips, Michael A. Goetz, Scott K. Smith, Deborah L. Zink, Jon Polishook, Russell Onishi, Scott Salowe, Judyann Wiltsie, John Allocco, Janet Sigmund, Karen Dorso, Suzy Lee, Stephen Skwish, Mercedes de la Cruz, Jesús Martín, Francisca Vicente, Olga Genilloud, Jun Lu, Ronald E. Painter, Katherine Young, Karen Overbye, Robert G.K. Donald, and Sheo B. Singh (2011) Discovery of Kibdelomycin, A Potent New Class of Bacterial Type II Topoisomerase Inhibitor by Chemical-Genetic Profiling in Staphylococcus aureus. Chemistry & Biology 18, 955–965.
  • Salud Sánchez Márquez, Gerald F. Bills, Noemí Herrero, Íñigo Zabalgogeazcoa (2011) Non-systemic fungal endophytes of grasses. Fungal Ecology doi:10.1016/j.funeco2010.12.001
  • Carmen Schleissner, Marta Pérez, Alejandro Losada, Pilar Rodríguez, Cristina Crespo, Paz Zúñiga, Rogelio Fernández, Fernando Reyes, and Fernando de la Calle (2011) Antitumor Actinopyranones Produced by Streptomyces albus POR-04-15-053 Isolated from a Marine Sediment. J. Nat. Prod. 74, 1590–1596
  • Marina Sánchez-Hidalgo, Manuel Montalbán-López, Rubén Cebrián, Eva Valdivia, Manuel Martínez-Bueno, Mercedes Maqueda (2011) AS-48 bacteriocin: close to perfection. Cell. Mol. Life Sci. 68:2845–2857
  • Anamariela Tijerino, R. Elena Cardoza, Javier Moraga, Mónica G. Malmierca, Francisca Vicente, Josefina Aleu, Isidro G. Collado, Santiago Gutiérrez, Enrique Monte a, Rosa Hermosa. (2011) Overexpression of the trichodiene synthase gene tri5 increases trichodermin production and antimicrobial activity in Trichoderma brevicompactum Fungal Genetics and Biology 48:285–296

 

2010

 

  • Ayers, S, Zink, DL, Mohn, K, Powell, JS, Brown, CM, Bills, G, Grund, A, Thompson, D and Singh, SB (2010) Anthelmintic constituents of Clonostachys candelabrum. Journal of Antibiotics 63, 119-122.
  • Cueva, C, Victoria Moreno-Arribas, M, Martín-Alvarez, PJ, Bills, G, Francisca Vicente, M, Basilio, A, Lopez Rivas, C, Requena, T, Rodriguez, JM and Bartolome, B (2010) Antimicrobial activity of phenolic acids against commensal, probiotic and pathogenic bacteria. Research in Microbiology 161, 372-382.
  • Duetz, W, Chase, M and Bills, G (2010) Miniaturization of fermentations. In Manual of Industrial Microbiology and Biotechnology, 3rd ed eds. Demain, A, Davies, J and Baltz, R. pp.99-116. Washington, DC: ASM Press.
  • Goetz, MA, Zhang, C, Zink, DL, Arocho, M, Vicente, F, Bills, GF, Polishook, J, Dorso, K, Onishi, R, Gill, C, Hickey, E, Lee, S, Ball, R, Skwish, S, Donald, RGK, Phillips, JW and Singh, SB (2010) Coelomycin, a highly substituted 2,6-dioxo-pyrazine fungal metabolite antibacterial agent discovered by Staphylococcus aureus fitness test profiling. Journal of Antibiotics 63, 512-518.
  • Márquez, SS, Bills, GF, Acuna, LD and Zabalgogeazcoa, I (2010) Endophytic mycobiota of leaves and roots of the grass Holcus lanatus. Fungal Diversity 41, 115-123.
  • Martín, MJ, Fernandez, R, Francesch, A, Amade, P, Matos-Pita, SSd, Reyes, F and Cuevas, C (2010) Plumisclerin A, a diterpene with a new skeleton from the soft coral Plumigorgia terminosclera. Organic Letters 12, 912-914.
  • Peterson, SW, Jurjevic, Z, Bills, GF, Stchigel, AM, Guarro, J and Vega, FE (2010) Genus Hamigera, six new species and multilocus DNA sequence based phylogeny. Mycologia 102, 847-864.
  • Reyes, F, Rodriguez-Acebes, R, Fernandez, R, Bueno, S, Francesch, A and Cuevas, C (2010) Stolonoxides E and F, cytotoxic metabolites from the marine ascidian Stolonica socialis. Journal of Natural Products 73, 83-85.

 

2009

 

  • Bills, G, Overy, DP, Genilloud, O and Peláez, F (2009) Contributions of pharmaceutical antibiotic and secondary metabolite discovery to the understanding of microbial defense and antagonism. In Defensive Mutualism in Microbial Symbiosis eds. White, JF and Torres, MS. pp.257-297. Boca Raton, USA: CRC Press.
  • Bills, GF, Martín, J, Collado, J, Platas, G, Overy, D, Tormo, JR, Vicente, F, Verkleij, G and Crous, P (2009) Measuring the distribution and diversity of antibiosis and secondary metabolites in the filamentous fungi. Society of Industrial Microbiology News 59, 133-147.
  • Bills, GF, Platas, G, Overy, D, Collado, J, Fillola, A, Jiménez, MR, Martín, J, Val, AGd, Vicente, F, Tormo, JR, Peláez, F, Calati, K, Harris, G, Parish, C, Xu, D and Roemer, T (2009) Discovery of the parnafungins, antifungal metabolites that inhibit mRNA poly-adenylation, from the Fusarium larvarum complex and other hypocrealean fungi. Mycologia 101, 445-469.
  • Blanco, MN, Moreno, G, Checa, J, Platas, G and Peláez, F (2009) Taxonomic and phylogenetic revision of Coniophora arachnoidea, C. opuntiae, and C. prasinoides. Mycotaxon 108, 467-477.
  • Coello, L, Martín, MJ and Reyes, F (2009) 1,5-diazacyclohenicosane, a new cytotoxic metabolite from the marine sponge Mycale sp. Marine Drugs 7, 445-450.
  • Donald, RGK, Skwish, S, Forsyth, RA, Anderson, JW, Zhong, T, Burns, C, Lee, S, Meng, X, LoCastro, L, Jarantow, LW, Martin, J, Lee, SH, Taylor, I, Robbins, D, Malone, C, Wang, LS, Zamudio, CS, Youngman, PJ and Phillips, JW (2009) A Staphylococcus aureus fitness test platform for mechanism-based profiling of antibacterial compounds. Chemistry & Biology 16, 826-836.
  • Genilloud, O (2009) Genus Micromonospora. In Bergey's Manual of Systematic Bacteriology, Volume 5 (Actinobacteria) eds. Busse, H-J, Goodfellow, M, Kämpfer, P, Ludwig, W, Suzuki, K and Whitman, WB. p. in press.
  • Genilloud, O (2009) Sudorder XI. Micromonosporineae and The family Micromonosporaceae. In Bergey's Manual of Systematic Bacteriology, Volume 5 (Actinobacteria) eds. Busse, H-J, Goodfellow, M, Kämpfer, P, Ludwig, W, Suzuki, K and Whitman, WB. p. in press.
  • Herath, K, Harris, G, Jayasuriya, H, Zink, D, Smith, S, Vicente, F, Bills, G, Collado, J, González, A, Jiang, B, Kahn, JN, Galuska, S, Giacobbe, R, Abruzzo, G, Hickey, E, Liberator, P, Xu, DM, Roemer, T and Singh, SB (2009) Isolation, structure and biological activity of phomafungin, a cyclic lipodepsipeptide from a widespread tropical Phoma sp. Bioorganic & Medicinal Chemistry 17, 1361-1369.
  • Laville, R, Genta-Jouve, G, Urda, C, Fernandez, R, Thomas, O, Reyes, F and Amade, P (2009) Njaoaminiums A, B, and C: Cyclic 3-alkylpyridinium salts from the marine sponge Reniera sp. Molecules 14, 4716-4724.
  • Ondeyka, J, Harris, G, Zink, D, Basilio, A, Vicente, F, Bills, G, Platas, G, Collado, J, González, A, de la Cruz, M, Martin, J, Kahn, JN, Galuska, S, Giacobbe, R, Abruzzo, G, Hickey, E, Liberator, P, Jiang, B, Xu, DM, Roemer, T and Singh, SB (2009) Isolation, structure elucidation, and biological activity of virgineone from Lachnum virgineum using the genome-wide Candida albicans fitness fest. Journal of Natural Products 72, 136-141.
  • Overy, D, Calati, K, Kahn, JN, Hsu, M-J, Martin, J, Collado, J, Roemer, T, Harris, G and Parish, CA (2009) Isolation and structure elucidation of parnafungins C and D, isoxazolidinone-containing antifungal natural products. Bioorganic & Medicinal Chemistry Letters 19, 1224-1227.
  • Oves-Costales, D, Kadi, N and Challis, GL (2009) The long-overlooked enzymology of a nonribosomal peptide synthetase-independent pathway for virulence-conferring siderophore biosynthesis. Chemical Communications, 6530-6541.
  • Oves-Costales, D, Song, L and Challis, GL (2009) Enantioselective desymmetrisation of citric acid catalysed by the substrate-tolerant petrobactin biosynthetic enzyme AsbA. Chemical Communications, 1389-1391.
  • Parish, CA, de la Cruz, M, Smith, SK, Zink, D, Baxter, J, Tucker-Samaras, S, Collado, J, Platas, G, Bills, G, Díez, MT, Vicente, F, Peláez, F and Wilson, K (2009) Antisense-guided isolation and structure elucidation of pannomycin, a substituted cis-decalin from Geomyces pannorum. Journal of Natural Products 72, 59-62.
  • Pérez, M, Crespo, C, Schleissner, C, Rodriguez, P, Zuniga, P and Reyes, F (2009) Tartrolon D, a cytotoxic macrodiolide from the marine-derived actinomycete Streptomyces sp. MDG-04-17-069. Journal of Natural Products 72, 2192-2194.
  • Pérez-Victoria, I, Kemper, S, Patel, MK, Edwards, JM, Errey, JC, Primavesi, LF, Paul, MJ, Claridge, TDW and Davis, BG (2009) Saturation transfer difference NMR reveals functionally essential kinetic differences for a sugar-binding repressor protein. Chemical Communications, 5862-5864.
  • Platas, G, González, V, Collado, J, Martín, J, Montes, C and Peláez, F (2009) Ascription of poorly defined taxa to taxonomic entities using molecular phylogenies: a case study on Nodulisporium sp producers of nodulisporic acid. Mycotaxon 109, 443-460.
  • Rojas, JL, Martín, J, Tormo, JR, Vicente, F, Brunati, M, Ciciliato, I, Losi, D, Trappen, SV, Mergaert, J, Swings, J, Marinelli, F and Genilloud, O (2009) Bacterial diversity from benthic mats of Antarctic lakes as a source of new bioactive metabolites Marine Genomics 2, 33-41.
  • Schmelz, S, Kadi, N, McMahon, SA, Song, L, Oves-Costales, D, Oke, M, Liu, H, Johnson, KA, Carter, LG, Botting, CH, White, MF, Challis, GL and Naismith, JH (2009) AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis. Nature Chemical Biology 5, 174-182.
  • Singh, SB, H. Jayasuriya, D. Zink, A. Basilio, F. Vicente, J. Collado, G. Bills, M. Lee Goldman, M. Motyl, J. Huber, G. Dezeny & K. Byrne (2009) Discovery and antibacterial activity of glabramycin A-C from Neosartorya glabra by an antisense strategy. Journal of Antibiotics 62, 265-269.
  • Singh, SB, Genilloud, O and Peláez, F (2009) NP structural diversity II - Secondary metabolite sources, evolution and selected molecular structures: Terrestrial micro-organisms – bacteria. In Comprehensive Natural Products Chemistry II eds. Moore, B and Crews, P. pp.109-140. UK: Elsevier.
  • Singh, SB, Zink, DL, Dorso, K, Motyl, M, Salazar, O, Basilio, A, Vicente, F, Byrne, KM, Ha, S and Genilloud, O (2009) Isolation, structure, and antibacterial activities of lucensimycins D-G, discovered from Streptomyces lucensis MA7349 using an antisense strategy. Journal of Natural Products 72, 345-352.
  • Vicente, F, Basilio, A, Platas, G, Collado, J, Bills, GF, González del Val, A, Martín, J, Tormo, JR, Harris, GH, Zink, DL, Justice, M, Kahn, JN and Peláez, F (2009) Distribution of the antifungal agents sordarins across filamentous fungi. Mycological Research 113, 754-770.
  • Zhang, C, Ondeyka, JG, Zink, DL, Basilio, A, Vicente, F, Salazar, O, Genilloud, O, Dorso, K, Motyl, M, Byrne, K and Singh, SB (2009) Discovery of okilactomycin and congeners from Streptomyces scabrisporus by antisense differential sensitivity assay targeting ribosomal protein S4. Journal of Antibiotics 62, 55-61.
  • Zhang, CW, Ondeyka, JG, Zink, DL, Basilio, A, Vicente, F, Collado, J, Platas, G, Huber, J, Dorso, K, Motyl, M, Byrne, K and Singh, SB (2009) Isolation, structure and antibacterial activity of pleosporone from a pleosporalean ascomycete discovered by using antisense strategy. Bioorganic & Medicinal Chemistry 17, 2162-2166.

 

2008

 

  • Ayers, S, Zink, DL, Powell, JS, Brown, CM, Grund, A, Bills, GF, Platas, G, Thompson, D and Singh, SB (2008) Noreupenifeldin, a tropolone from an unidentified ascomycete. Journal of Natural Products 71, 457-459.
  • Bills, GF, Platas, G, Fillola, A, Jiménez, MR, Collado, J, Vicente, F, Martín, J, González, A, Bur-Zimmermann, J, Tormo, JR and Peláez, F (2008) Enhancement of antibiotic and secondary metabolite detection from filamentous fungi by growth on nutritional arrays. Journal of Applied Microbiology 104, 1644-1658.
  • Ciulli, A, Scott, DE, Ando, M, Reyes, F, Saldanha, SA, Tuck, KL, Chirgadze, DY, Blundell, TL and Abell, C (2008) Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate. ChemBiochem 9, 2606-2611.
  • Fernandez, L, Banuelos, O, Zafra, A, Ronchel, C, Perez-Victoria, I, Morales, JC, Velasco, J and Adrio, JL (2008) Alteration of substrate specificity of Galactomyces geotrichum BT107 lipase I on eicosapentaenoic acid-rich triglycerides. Biocatalysis and Biotransformation 26, 296-305.
  • Fernandez, R, Martín, MJ, Rodriguez-Acebes, R, Reyes, F, Francesch, A and Cuevas, C (2008) Diazonamides C-E, new cytotoxic metabolites from the ascidian Diazona sp. Tetrahedron Letters 49, 2283-2285.
  • Jiang, B, Xu, DM, Allocco, J, Parish, C, Davison, J, Veillette, K, Sillaots, S, Hu, WQ, Rodriguez-Suarez, R, Trosok, S, Zhang, L, Li, Y, Rahkhoodaee, F, Ransom, T, Martel, N, Wang, H, Gauvin, D, Wiltsie, J, Wisniewski, D, Salowe, S, Kahn, JN, Hsu, MJ, Giacobbe, R, Abruzzo, G, Flattery, A, Gill, C, Youngman, P, Wilson, K, Bills, G, Platas, G, Peláez, F, Díez, MT, Kauffman, S, Becker, J, Harris, G, Liberator, P and Roemer, T (2008) PAP inhibitor with in vivo efficacy identified by Candida albicans genetic profiling of natural products. Chemistry & Biology 15, 363-374.
  • Kadi, N, Arbache, S, Song, L, Oves-Costales, D and Challis, GL (2008) Identification of a gene cluster that directs putrebactin biosynthesis in Shewanella species: PubC catalyzes cyclodimerization of N-hydroxy-N-succinylputrescine. Journal of the American Chemical Society 130, 10458-10459.
  • Laville, R, Thomas, OP, Berrue, F, Reyes, F and Amade, P (2008) Pachychalines A-C : Novel 3-alkylpyridinium salts from the marine sponge Pachychalina sp. European Journal of Organic Chemistry 2008, 121-125.
  • Moreno, G, Platas, G, Peláez, F, Bernedo, M, Vargas, A, Daza, A, Santamaria, C, Camacho, M, de la Osa, LR and Manjon, JL (2008) Molecular phylogenetic analysis shows that Amanita ponderosa and A. curtipes are distinct species. Mycological Progress 7, 41-47.
  • Ortega, A, Moreno, G, Platas, G and Peláez, F (2008) A new Armillaria mellea variant from tops of coastal sand dunes in southern Spain. Mycotaxon 104, 349–364.
  • Oves-Costales, D, Kadi, N, Fogg, MJ, Song, L, Wilson, KS and Challis, GL (2008) Petrobactin biosynthesis: AsbB catalyzes condensation of spermidine with N8-citryl-spermidine and its N1-(3,4-dihydroxybenzoyl) derivative. Chemical Communications, 4034-4036.
  • Parish, CA, Smith, SK, Calati, K, Zink, D, Wilson, K, Roemer, T, Jiang, B, Xu, DM, Bills, G, Platas, G, Peláez, F, Díez, MT, Tsou, N, McKeown, AE, Ball, RG, Powles, MA, Yeung, L, Liberator, P and Harris, G (2008) Isolation and structure elucidation of parnafungins, antifungal natural products that inhibit mRNA polyadenylation. Journal of the American Chemical Society 130, 7060-7066.
  • Peláez, F, González, V, Platas, G, Sánchez-Ballesteros, J and Rubio, V (2008) Molecular phylogenetic studies within the Xylariaceae based on ribosomal DNA sequences. Fungal Diversity 31, 111-134.
  • Pérez-Victoria, I, Zafra, A and Morales, JC (2008) Positive-ion ESI mass spectrometry of regioisomeric nonreducing oligosaccharide fatty acid monoesters: In-source fragmentation of sodium adducts. Journal of Mass Spectrometry 43, 633-638.
  • Poza, JJ, Fernandez, R, Reyes, F, Rodriguez, J and Jiménez, C (2008) Isolation, biological significance, synthesis, and cytotoxic evaluation of new natural parathiosteroids A-C and analogues from the soft coral Paragorgia sp. journal of Organic Chemistry 73, 7978-7984.
  • Reyes, F, Fernandez, R, Rodriguez, A, Bueno, S, Eguilior, Cd, Francesch, A and Cuevas, C (2008) Cytotoxic staurosporines from the marine ascidian Cystodytes solitus. Journal of Natural Products 71, 1046-1048.
  • Reyes, F, Fernández, R, Rodriguez, A, Francesch, A, Taboada, S, Avila, C and Cuevas, C (2008) Aplicyanins A-F, new cytotoxic bromoindole derivatives from the marine tunicate Aplidium cyaneum. Tetrahedron 64, 5119-5123.
  • Rincón, A, Arenal, F, González, I, Manrique, E, Lucas, MM and Pueyo, JJ (2008) Diversity of rhizobial bacteria isolated from nodules of the gypsophyte Ononis tridentata L. growing in Spanish soils. Microbial Ecology 56, 223-233.
  • Rincón, A, Arenal, F, González, I, Manrique, E, Lucas, MM and Pueyo, JJ (2008) Diversity of rhizobial bacteria isolated from nodules of the gypsophyte Ononis tridentata L. growing in spanish soils. Microbial Ecology 56, 223-233.
  • Rossman, AY, Farr, DF, Platas, G and Newcombe, G (2008) Hydropisphaera fungicola Rossman, Farr & Newcombe sp. nov. Fungal Planet 24.
  • Ruibal, C, Platas, G and Bills, GF (2008) High diversity and morphological convergence among melanised fungi from rock formations in the Central Mountain System of Spain. Persoonia 21, 93-110.
  • Sánchez, S, Bills, GF and Zabalgogeazcoa, I (2008) Fungal endophytes from two sympatric coastal grasses. Fungal Diversity 33, 87-100.
  • Singh, SB, Zink, DL, Herath, KB, Salazar, O and Genilloud, O (2008) Discovery and antibacterial activity of lucensimycin C from Streptomyces lucensis. Tetrahedron Letters 49, 2616-2619.
  • Zhang, CW, Occi, J, Masurekar, P, Barrett, JF, Zink, DL, Smith, S, Onishi, R, Ha, SH, Salazar, O, Genilloud, O, Basilio, A, Vicente, F, Gill, C, Hickey, EJ, Dorso, K, Motyl, M and Singh, SB (2008) Isolation, structure, and antibacterial activity of philipimycin, a thiazolyl peptide discovered from Actinoplanes philippinensis MA7347. Journal of the American Chemical Society 130, 12102-12110.
  • Zhang, CW, Ondeyka, JG, Zink, DL, Basilio, A, Vicente, F, Collado, J, Platas, G, Bills, G, Huber, J, Dorso, K, Motyl, M, Byrne, K and Singh, SB (2008) Isolation, structure, and antibacterial activity of phaeosphenone from a Phaeosphaeria sp discovered by antisense strategy. Journal of Natural Products 71, 1304-1307.